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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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What is Viagra?

The Viagra brand name is made by Pfizer Inc., and there are three different versions of Viagra available in the market: the brand name, which is produced by GlaxoSmithKline, the generic version is a generic version of Viagra. They have the same active ingredients as Viagra, and the same effect on the body.

The active ingredient in Viagra is sildenafil. It is a phosphodiesterase type 5 inhibitor that is prescribed to treat erectile dysfunction (ED) in men. Sildenafil belongs to a group of medicines called phosphodiesterase type 5 inhibitors.

There are two types of sildenafil: “active” and “inactive”.

Sildenafil inhibits an enzyme called PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP causes smooth muscle relaxation and vasodilation, thereby enhancing blood flow to the penis. This action helps men to achieve and maintain an erection.

It is used to treat pulmonary arterial hypertension (PAH) by relaxing blood vessels in the lungs, which helps to prevent pulmonary hypertension from developing.

Viagra is taken as needed, usually around 30 minutes before sexual activity. It is important to note that sexual stimulation is not necessary for the medication to work.

How does Viagra work?

Viagra works by inhibiting the enzyme phosphodiesterase type 5, which breaks down cGMP in the penis. By blocking this enzyme, sildenafil improves blood flow to the penis and helps men achieve and maintain an erection.

How is Viagra used?

Viagra is taken only as a single dose. It is important to take the medication with a high-fat meal around 30 minutes before engaging in sexual activity. This helps to ensure that the medication is absorbed into the body and that it does not interact negatively with some other medications.

How long does it take Viagra to work?

Viagra starts to work within 30 minutes of taking it. This is because sildenafil enhances the effects of nitric oxide, a chemical that relaxes blood vessels in the penis. This results in increased blood flow to the penis and improved erections.

Sildenafil is typically taken daily, as needed, for several weeks. It is important to take Viagra daily, as it may cause side effects such as headaches, dizziness, and flushing. The medication can also interact with other medications, such as certain blood pressure medicines, and may cause other adverse effects.

Viagra can cause more serious side effects, including:

If you are taking any other medications, including those you take in combination with Viagra, you should seek medical attention right away. If you experience any of the following symptoms, seek medical attention immediately: chest pain, shortness of breath, or fainting. This is known as a mild allergic reaction.

If you have any other medical conditions, such as heart problems, high blood pressure, low potassium levels, or a history of heart attack or stroke, you should seek medical help right away. If you have low blood pressure, you should seek medical help right away. You should also seek medical help if you notice any unusual symptoms of a heart attack, stroke, chest pain, or irregular heartbeat.

Viagra is not recommended for use if you have certain medical conditions, such as heart disease, high blood pressure, or a history of stroke or blood clot. If you are pregnant or breastfeeding, you should consult your doctor before taking Viagra.

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Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Viagra use include:

  • Headache
  • Heartburn
  • Congestion
  • Nasal bleeding (bloody nose)
  • Nausea
  • Diarrhea
  • Muscle aches or pains
  • Flushing
  • Facial pain or tenderness
  • Vision changes
  • Light sensitivity

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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  • Viagra has not been shown to cause any severe side effects. However, like all medications, it may cause some side effects. The information below may be useful to you. If you are considering using Viagra, let your doctor know before using it.
  • Viagra may cause some side effects to be reported by people who are taking nitrates. Examples of nitrates that you can take are isosorbide, isosorbide mononitrate, and metoprolol. Some examples of isosorbide mononitrate that you can take are atenolol, doanosine, and together with sotalol. Some examples of drugs that you should not take are nitroglycerin, tamsulosin, and terbutaline. Some drugs that you should not take are may be causing side effects.
  • Tell your health care provider if you are taking any of the following medications: lisinopril, ramipril, losartan, or rivaroxaban.
  • Tell your health care provider if you are taking guanylate cyclase stimulators such as a cyclophosphamide, methotrexate, or adalat.
  • If you are taking nitrates for chest pain, shock, or heart failure, you should inform your health care provider if you are taking nitroglycerin, tamsulosin, or aspigma1016.
  • If you are taking a nitrate drug for chest pain, shock, or heart failure, you should let your doctor know if you are taking guanylate cyclase stimulators such as a cyclophosphamide, methotate, or adalat.
  • If you are taking a nitrate drug for chest pain, shock, or heart failure, you should let your health care provider know if you are taking guanylate cyclase stimulators such as a cyclophosphamide, methotate, or adalat.
  • As with all prescription medications, inform your doctor about any heart problems you are currently managing. If you currently have a condition that makes you unfit to drive, they may recommend that you use a lower-strength alternative.

    In addition, let your doctor know if you have recently had a heart surgery or are at risk for heart surgery.